From Heartbreak to Hope - A Genome Foundation Success Story

From Heartbreak to Hope – A Genome Foundation Success Story

Dec 08, 2025

A couple in their early 40s came to Genome Foundation after a miscarriage caused by Trisomy 21 (Down syndrome) and years of failed attempts to conceive. A comprehensive genetic and fertility evaluation revealed multiple hidden factors oligospermia, semen infection, low Vitamin D3, anaemia, and a homozygous MTHFR mutation in both partners.

At Genome Foundation, they received a genetics-guided treatment plan:
✔ Vitamin D3 & biochemical corrections
✔ Infection treatment & antioxidants
✔ Haematinics for the female partner
✔ Ovulation induction at optimal timing
✔ Nutrition & lifestyle changes tailored to MTHFR mutation
✔ Believing and applying Integrated medicine approaches: diet, yoga, Ayurveda & allopathy to this kind of unusual problem.

With close monitoring and personalized care under the guidance of Dr Kanaka Bhushanam, the couple made steady progress.

The breakthrough:
In July 2025, they conceived successfully a moment that transformed years of struggle into joy.

Their journey proves:
✨ Parenthood in the 40s is possible
✨ Genetic testing uncovers key barriers
✨ Consistent guidance can turn despair into hope

At Genome Foundation, we combine science, compassion & precision medicine to help families achieve their dream of parenthood.